Products Description
Epichlorohydrin is an organochlorine compound and epoxide widely used as an industrial solvent. With high chemical reactivity, it serves as a key raw maleic-anhydride.html">material for manufacturing glycerol, plastics, epoxy adhesives, resins, and elastomers. It is also used in producing glycidyl nitrate and alkali metal chlorides, acts as a solvent for cellulose, resins, and coatings, and functions as an insect fumigant. In biochemistry, it is applied as a crosslinking agent for preparing Sephdex size‑exclusion chromatography resins. It is classified as a potential carcinogen and may cause adverse effects on the respiratory tract and kidneys. It can be synthesized through the reaction of allyl chloride with hypochlorous acid and alcohols.
Chemical Properties
| Item | Specification |
| Melting point | -57 °C |
| alpha | -1～+1°(D/20℃)(c=1,CH3OH) |
| Boiling point | 115-117 °C(lit.) |
| density | 1.183 g/mL at 25 °C(lit.) |
| vapor density | 3.2 (vs air) |
| vapor pressure | 13.8 mm Hg (21.1 °C) |
| refractive index | n20/D 1.438(lit.) |
| Fp | 93 °F |
| storage temp. | Store below +30°C. |
| solubility | 65.9g/l |
| form | Liquid |
| color | APHA: ≤20 |
| Specific Gravity | 1.183 (20/4℃) |
| Odor | Pungent, garlic; sweet, pungent; like chloroform. |
| explosive limit | 3.8-21%(V) |
| Water Solubility | 6 g/100 mL (10 ºC) |
| FreezingPoint | -57.2℃ |
| Merck | 14,3611 |
| BRN | 79785 |
| Henry's Law Constant | 3.42(x 10-5 atm·m3/mol) at 25 °C (static headspace-GC, Welke et al., 1998) |
| Exposure limits | TLV-TWA(skin) 8 mg/m3 (2 ppm) (ACGIH); STEL (15 min) 19 mg/m3 (5 ppm) (NIOSH). |
| Dielectric constant | 22.9（20℃） |
| Stability | Unstable. Flammable - note wide explosion limits and low flash point. |
| LogP | 0.45 at 20℃ |
| CAS DataBase Reference | 106-89-8(CAS DataBase Reference) |
| IARC | 2A (Vol. 11, Sup 7, 71) 1999 |
| NIST Chemistry Reference | Oxirane, (chloromethyl)-(106-89-8) |
| EPA Substance Registry System | Epichlorohydrin (106-89-8) |
Safety Information
| Item | Specification |
| Hazard Codes | T |
| Risk Statements | 45-10-23/24/25-34-43 |
| Safety Statements | 53-45 |
| RIDADR | UN 2023 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TX4900000 |
| Autoignition Temperature | 779 °F |
| TSCA | Yes |
| HS Code | 2910 30 00 |
| HazardClass | 6.1 |
| PackingGroup | II |
| Hazardous Substances Data | 106-89-8(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 0.09 g/kg (Smyth, Carpenter) |
| IDLA | 75 ppm |
Product Application
Bisphenol A epoxy resins are produced from epichlorohydrin and bisphenol A, forming bisphenol‑A diglycidyl ether, the basic monomer of such epoxy resins. Sensitization to epichlorohydrin is most common among workers in the epoxy resin industry, while cases among the general public are rare. Reported non‑occupational cases include exposure to soil fumigants, solvent cements, and pharmaceutical manufacturing workers involved in drug synthesis. Epichlorohydrin was used in producing propranolol and oxprenolol.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
