N,N-Dimethylformamide CAS 68-12-2

Chemical Name: N,N-Dimethylformamide

Common Abbreviation: DMF

CAS Registry Number: 68-12-2

Molecular Formula: C₃H₇NO

Molecular Weight: 73.11

Synonyms: N,N-Dimethylmethanamide, Neutral Marker for Capillary

Product Grade & Purity: ACS Grade, Purity ≥ 99.8%

Standard Laboratory Packaging: 4 × 25 mL

Appearance: Colorless transparent liquid

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Products Description

This product is a flammable liquid that emits a distinctive fishy and amine-like odor at low concentrations, with an odor threshold ranging from 0.47 ppm to 100 ppm.

Key physical parameters:

  • Melting Point: -61 °C
  • Boiling Point: 153 °C
  • Specific Gravity: 0.95 (relative to water, 1:1)
  • Vapor Pressure: 3 mmHg at 20 °C
  • Flash Point: 58 °C
  • Autoignition Temperature: 444.5 °C

Combustion & explosion characteristics (tested at 100 °C):

  • Lower Explosive Limit (LEL): 2.2%
  • Upper Explosive Limit (UEL): 15.2%

NFPA 704 Hazard Rating: Health 2, Flammability 2, Reactivity 0

Solubility Performance: Completely miscible with water, and highly compatible with most conventional organic solvents. It features stable chemical properties under normal ambient conditions and is a typical polar aprotic solvent.

N,N-Dimethylformamide

Chemical Properties

ItemSpecification
Melting point-61 °C (lit.)
alpha0.94 º
Boiling point153 °C (lit.)
density0.944 g/mL (lit.)
vapor density2.5 (vs air)
vapor pressure2.7 mm Hg (20 °C)
refractive indexn20/D 1.430(lit.)
Fp136 °F
storage temp.Store at +5°C to +30°C.
solubilitywater miscible
pka-0.44±0.70(Predicted)
formliquid
colorAPHA: ≤15
Appearancecolorless liquid
PH7 (200g/l, H2O, 20℃)
OdorFaint, ammonia-like odor detectable at 100 ppm
Relative polarity0.386
Odor Threshold1.8ppm
explosive limit2.2-16%(V)
Water Solubilitysoluble
λmaxλ: 270 nm Amax: 1.00 λ: 275 nm Amax: 0.30 λ: 295 nm Amax: 0.10 λ: 310 nm Amax: 0.05 λ: 340-400 nm Amax: 0.01
SensitiveHygroscopic
Merck14,3243
BRN605365
Exposure limitsNIOSH REL: TWA 10 ppm (30 mg/m3), IDLH 500 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted).
Dielectric constant36.71
InChIKeyZMXDDKWLCZADIW-UHFFFAOYSA-N
LogP-1.010
Surface tension35.20mN/m at 298.15K
Surface tension37.1mN/m at 20°C
CAS DataBase Reference68-12-2(CAS DataBase Reference)
NIST Chemistry ReferenceFormamide, N,N-dimethyl-(68-12-2)
IARC2A (Vol. 47, 71, 115) 2018
EPA Substance Registry SystemN,N-Dimethylformamide (68-12-2)

Safety Information

ItemSpecification
Hazard CodesT
Risk Statements61-20/21-36
Safety Statements53-45
RIDADRUN 2265 3/PG 3
OEBA
OELTWA: 10 ppm (30 mg/m3) [skin]
WGK Germany1
RTECSLQ2100000
F3-10
Autoignition Temperature445 °C
Hazard NoteToxic
TSCAYes
HazardClass3
PackingGroupIII
HS Code29241990
Hazardous Substances Data68-12-2(Hazardous Substances Data)
ToxicityLD50 in mice, rats (ml/kg): 6.8, 7.6 orally; 6.2, 4.7 i.p. (Bartsch)
IDLA500 ppm

Product Application

With excellent universal solubility, N,N-Dimethylformamide serves as a high-efficiency industrial solvent, functional additive and chemical synthesis intermediate, and has been widely adopted in multiple manufacturing fields.

It is commonly used for the processing of polymer fibers, thin films and various surface coating materials. It can optimize the production process and ensure stable spinning of acrylic fibers, and is also a key material for manufacturing wire enamels. In the pharmaceutical industry, it is widely utilized as a crystallization medium in drug synthesis and preparation procedures.

Supply & Delivery

Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days

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