Sodium carboxyl methylstarch

CAS Number 9063-38-1

Chemical Formula C2H4O3·xNa·x

Synonyms

SODIUM STARCH GLYCOLATE

sodium carboxyl methylstarch

Primojel

Appearance White Powder

MOQ Minimum Order Quantity 1 FCL Full Container Load

Product Details

Sodium carboxyl methylstarch CAS#9063-38-1

Sodium starch glycolate appears as a white or nearly white, free-flowing powder with high hygroscopicity. As described in PhEur 6.0, microscopic observation reveals irregular, ovoid, or pear-shaped granules ranging from 30 to 100 micrometers, or round granules 10 to 35 micrometers; compound granules with 2–4 units appear occasionally. Granules feature an eccentric hilum and distinct concentric striations. Under polarized light, a clear black cross intersects at the hilum, with tiny crystals on granule surfaces. The granules swell significantly when exposed to water.

Sodium carboxyl methylstarch

Sodium carboxyl methylstarch Chemical Properties

ItemValue
Melting point>210 °C dec.
storage temp.Inert atmosphere Room Temperature
solubilityPractically insoluble in methylene chloride It gives a translucent suspension in water
formSolid
colorWhite to Off-White
maleic-anhydride.html">Major Applicationpharmaceutical small molecule
Cosmetics Ingredients FunctionsEMULSION STABILISING BINDING VISCOSITY CONTROLLING FILM FORMING
CAS DataBase Reference9063-38-1
EPA Substance Registry SystemStarch carboxymethyl ether sodium salt 9063-38-1

Safety Information

ItemValue
WGK Germany1
TSCATSCA listed
HS Code3505100092
Storage Class11 Combustible Solids

Product Application of Sodium carboxyl methylstarch CAS#9063-38-1

Sodium starch glycolate is extensively used in oral medicines as a disintegrant for capsules and tablets. It works well in tablets made by direct compression or wet granulation. Typical usage levels are 2%–8%, with an optimal dose around 4%; 2% often suffices for many formulations. Disintegration happens through fast water absorption followed by quick, substantial expansion.

Unlike many disintegrants whose performance drops with hydrophobic additives like lubricants, sodium starch glycolate keeps strong disintegrating action. Higher tableting compression pressure also does not lengthen disintegration time.

Research has also explored its use as a suspending agent in liquid formulations.

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