4-Fluorobenzaldehyde

CAS Number: 459-57-4
Chemical Formula: C7H5FO
Synonyms:
Paroxetine Impurity 58
4-fluoro-benzaldehyd
Benzaldehyde, p-fluoro-
Appearance: Clear colorless to yellow Liquid
HS Code: 29130000
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details
4-Fluorobenzaldehyde (CAS#459-57-4) is a key organic synthesis intermediate. It normaleic-anhydride.html">mally appears as a colorless to light yellow liquid with a characteristic aromatic odor. It exhibits typical aldehyde group reactivity, supporting oxidation, reduction, condensation and similar reactions. Owing to its fluorine atom substituent, it shows unique reactivity and acts as a special reaction site in organic synthesis.4-Fluorobenzaldehyde

Parameters

ItemValue
Melting point-10 °C (lit.)
Boiling point181 °C/758 mmHg (lit.)
density1.157 g/mL at 25 °C (lit.)
vapor pressure19 hPa (70 °C)
refractive indexn20/D 1.521(lit.)
Fp134 °F
storage temp.Store below +30°C.
solubilityChloroform, Methanol
formLiquid
colorClear colorless to yellow
Specific Gravity1.157
Water SolubilityIMMISCIBLE
SensitiveAir Sensitive
BRN385857
Stability:Air Sensitive
InChIKeyUOQXIWFBQSVDPP-UHFFFAOYSA-N
CAS DataBase Reference459-57-4(CAS DataBase Reference)
NIST Chemistry ReferenceBenzaldehyde, 4-fluoro-(459-57-4)
EPA Substance Registry SystemBenzaldehyde, 4-fluoro- (459-57-4)

Safety Information

ItemDetails
Hazard CodesXi,F
Risk Statements36/37/38
Safety Statements26-36-37/39-36/37/39-27
RIDADRUN 1989 3/PG 3
WGK Germany2
F9-23
Hazard NoteFlammable
TSCAT
HazardClass3.2
PackingGroupIII
HS Code29130000

Product Application

4-Fluorobenzaldehyde is a fluorinated benzaldehyde that can inhibit mushroom tyrosinase. It is used in the synthesis of pyrazolopyridine derivatives, which act as mitogen-activated protein kinase (MAPK) inhibitors. It also functions as a vital building block for manufacturing various pharmaceutical ingredients.

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