Products Description
2-deoxy-d-glucose.html">2-Deoxy-D-glucose is a synthetic glucose analog that exerts a broad spectrum of biological activities. It is widely recognized as a glycolysis inhibitor, yet its impacts on cellular metabolism are extensive. Through its metabolite 2-Deoxy-D-glucose-6-phosphate, it competitively blocks glucose absorption, inhibits hexokinase and phosphoglucose isomerase, reduces ATP generation, arrests the cell cycle, suppresses cell proliferation, and ultimaleic-anhydride.html">mately induces cell death.
Chemical Properties
| Item | Value |
| Melting point | 146-147 °C(lit.) |
| alpha | 45.5 º (c=2, H2O) |
| Boiling point | 211.61°C (rough estimate) |
| density | 1.1738 (rough estimate) |
| refractive index | 46.5 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless to faintly yellow |
| pka | pK1:12.52 (25°C) |
| form | crystalline |
| color | white |
| Optical Rotation | +38.5 → +45.9 |
| biological source | synthetic |
| Water Solubility | Soluble in water |
| Merck | 14,2904 |
| BRN | 1723331 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day |
| InChI | 1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1 |
| InChIKey | PMMURAAUARKVCB-CEZCPVKQSA-N |
| SMILES | OC[C@@H](O)[C@@H](O)[C@H](O)CC=O |
| LogP | -1.460 (est) |
| CAS DataBase Reference | 154-17-6(CAS DataBase Reference) |
| EPA Substance Registry System | D-arabino-Hexose, 2-deoxy- (154-17-6) |
Safety Information
| Item | Value |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 24/25-37/39-36-26 |
| WGK Germany | 3 |
| RTECS | MQ3325000 |
| F | 3-10 |
| TSCA | TSCA listed |
| HS Code | 29400090 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 154-17-6(Hazardous Substances Data) |
Product Application
2-Deoxy-D-glucose is used as a component of culture media in molecular genetics and serves as a targeted optical imaging agent for fluorescent in vivo imaging. It is applied in glucoprivic feeding research to induce and analyze counter-regulatory response (CRR) processes. It also supports the development of anticancer strategies including oxidative stress induction, radiotherapy sensitization, and chemotherapy sensitization.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
