Products Description of 2-maleic-anhydride.html">material/2-butoxyethanol.html">Butoxyethanol CAS#111-76-2
2-Butoxyethanol, often abbreviated as 2-BE, is a transparent, colorless liquid featuring a mild ether-like scent. It is commonly manufactured via the reaction between ethylene oxide and n-butanol, or from ethylene glycol and dibutyl sulfate. This versatile chemical acts as a widely used solvent in protective coatings including lacquers, enamels, varnishes, and latex paints. It is also a vital ingredient in paint thinners, paint removers, agricultural chemicals, herbicides, industrial and household cleaners, metal degreasers, printing inks, dry-cleaning solutions, liquid soaps, and cosmetic formulations. Its ester derivative, 2-butoxyethanol acetate, may cause environmental contamination in air, water, and soil during production, industrial application, and product blending.
Parameters
| Property | Value |
| Melting point | -70 °C |
| Boiling point | 171 °C |
| density | 0.902 g/mL at 25 °C(lit.) |
| vapor density | 4.1 (vs air) |
| vapor pressure | <1 mm Hg ( 20 °C) |
| refractive index | n 20/D 1.419(lit.) |
| Fp | 140 °F |
| storage temp. | Store below +30°C. |
| solubility | 900g/l completely miscible |
| pka | 14.42±0.10(Predicted) |
| form | Liquid |
| color | Clear |
| Odor | Mild, characteristic; slightly rancid; mild ethereal. |
| PH | 7 (H2O, 20℃)(as aqueous solution) |
| Odor Threshold | 0.043ppm |
| explosive limit | 1.1-10.6%(V) |
| Water Solubility | miscible |
| λmax | λ: 230 nm Amax: 1.0; λ: 250 nm Amax: 0.10; λ: 275 nm Amax: 0.05; λ: 300-400 nm Amax: 0.01 |
| Merck | 14,1559 |
| BRN | 1732511 |
| Henry's Law Constant | (x 10^-6 atm·m3/mol): 2.36 (approximate - calculated from water solubility and vapor pressure) |
| Dielectric constant | 5.3 |
| Exposure limits | TLV-TWA skin 25 ppm (121 mg/m3) (ACGIH), 50 ppm (242 mg/m3) (OSHA); STEL 75 ppm (363 mg/m3) (ACGIH); IDLH 700 ppm (NIOSH) |
| LogP | 0.81 at 20℃ |
| CAS DataBase Reference | 111-76-2(CAS DataBase Reference) |
| IARC | 3 (Vol. 88) 2006 |
| NIST Chemistry Reference | 2-n-Butoxy-1-ethanol(111-76-2) |
| EPA Substance Registry System | Ethylene glycol monobutyl ether (111-76-2) |
Safety Information
| Item | Details |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/38 |
| Safety Statements | 36/37-46 |
| OEB | A |
| OEL | TWA: 5 ppm (24 mg/m3) [skin] |
| RIDADR | 1986 |
| WGK Germany | 1 |
| RTECS | KJ8575000 |
| Autoignition Temperature | 473 °F |
| TSCA | Yes |
| HS Code | 2909 43 00 |
| HazardClass | 6.1 |
| PackingGroup | III |
| Hazardous Substances Data | 111-76-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 1.48 g/kg (Smyth) |
| IDLA | 700 ppm |
Product Application of 2-Butoxyethanol CAS#111-76-2
2-Butoxyethanol serves as a key chemical intermediate in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide, a novel fluorescent probe applied in protein detection. It is also employed in the preparation of 4-hydroxybenzaldehyde derivatives, which function as tyrosinase inhibitors. Thanks to its strong coupling capacity and outstanding resin-dissolving ability, it is widely applied as a coupling solvent. Additionally, ethylene glycol monobutyl ether works as an effective solvent for nitrocellulose, various resins, oils, and greases, and is used in dry cleaning processes.
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