Levulinic acid

CAS Number: 123-76-2
Chemical Formula: C5H8O3
Synonyms:
2-Acetopropionicacid
4-oxovaleric
Appearance: Light Yellow Liquid
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details

Levulinic acid CAS#123-76-2
Levulinic acid features a tart, whiskey‑like flavor. It can be produced by reacting concentrated or dilute hydrochloric acid with sucrose, glucose, or fructose, which explains why it is found in caramelized products.Levulinic acid

Parameters

ItemValue
Melting point30-33 °C (lit.)
Boiling point245-246 °C (lit.)
density1.134 g/mL at 25 °C (lit.)
vapor pressure1 mm Hg (102 °C)
refractive indexn20/D 1.439(lit.)
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Fp280 °F
storage temp.Store below +30°C.
solubility675g/l
pkapKa 4.65(H2O,t = 25,c=0.03-0.001) (Uncertain)
formLiquid After Melting
colorClear yellow
Odorat 100.00 %. sweet caramel acidic acetoin buttery
Odor Typecaramellic
biological sourcesynthetic
Water SolubilitySoluble in water (675g/L at 20°C).
SensitiveLight Sensitive
Merck14,5472
JECFA Number606
BRN506796
Major Applicationcleaning products cosmetics flavors and fragrances food and beverages personal care
Cosmetics Ingredients FunctionsPERFUMING SKIN CONDITIONING
Cosmetic Ingredient Review (CIR)Levulinic acid (123-76-2)
InChI1S/C5H8O3/c1-4(6)2-3-5(7)8/h2-3H2,1H3,(H,7,8)
InChIKeyJOOXCMJARBKPKM-UHFFFAOYSA-N
SMILESCC(=O)CCC(O)=O
LogP-0.498
Surface tension42.53mN/m at 298.15K
CAS DataBase Reference123-76-2(CAS DataBase Reference)
NIST Chemistry ReferencePentanoic acid, 4-oxo-(123-76-2)
EPA Substance Registry SystemLevulinic acid (123-76-2)

Safety Information

ItemValue
Hazard CodesXn,C
Risk Statements22-36/37/38-34-R34-R22
Safety Statements26-45-36/37/39-S45-S36/37/39-S26
RIDADR3261
WGK Germany3
RTECSOI1575000
TSCATSCA listed
HazardClass8
PackingGroupIII
HS Code29183000
Storage Class13 - Non Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral Eye Dam. 1 Skin Sens. 1
ToxicityLD50 orally in Rabbit: 1850 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Product Application

Levulinic acid serves as a raw material for pharmaceuticals, fragrances, coatings, and solvents.
It is highly versatile: acting as both a carboxylic acid and a ketone, it undergoes esterification, halogenation, hydrogenation, oxidation, dehydrogenation, and condensation to form resins, medicines, flavors, solvents, rubber and plastic additives, lubricant additives, and surfactants. In pharma, its calcium salt supports bone health and normal neuromuscular function; it is also used in indomethacin and plant hormone production. Bisphenol acid derived from levulinic acid yields water‑soluble resins for paper filter applications. It is also a key intermediate for agrochemicals and dyes.
It is used in biochemical reagents and organic synthesis.
As an important industrial feedstock and solvent, it supports production of pharmaceuticals (IV formulations, indomethacin), resins (water‑soluble bisphenol acid resins), flavors (food and tobacco), coatings, pesticides, and surfactants.
It supports biochemical research, ester and drug manufacturing, and acts as a chlorophyll synthesis inhibitor.

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