Nicotinamide

CAS Number: 98-92-0
Chemical Formula: C6H6N2O
Synonyms:
Nicotinamide For Biochemistry
Nicotinamide B.P., U.S.P.
NIACINAMIDE USP GRANULAR
Appearance: White Powder
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details

Nicotinamide, also known as Vitamin B3 (niacinamide, nicotinic acid amide), is the amide form of nicotinic acid (pyridine-3-carboxylic acid). It is a water‑soluble vitamin that the body does not store. Dietary sources of this vitamin include nicotinamide, nicotinic acid, and tryptophan. Major natural sources of niacin include meat, liver, green leafy vegetables, wheat, oat, palm kernel oil, legumes, yeast, mushrooms, nuts, milk, fish, tea, and coffee.Nicotinamide

Parameters

PropertyValue
Melting point128-131 °C(lit.)
Boiling point150-160 °C
bulk density360kg/m3
density1.40
vapor density4.22 (vs air)
vapor pressure0Pa at 25℃
refractive index1.4660 (estimate)
Fp182 °C
storage temp.2-8°C
solubility691g/l
pka3.3(at 20℃)
formpowder
colorwhite
OdorOdorless
PH6.0-7.5 (50g/l, H2O, 20℃)
PH Range9
biological sourcesynthetic (organic)
Water Solubility1000 g/L (20 ºC)
Decomposition>=200 °C
Merck14,6523
BRN383619
BCS Class1
Stability:Stable. Incompatible with strong oxidizing agents.
Major Applicationcell analysis
Cosmetics Ingredients FunctionsSMOOTHING
Cosmetic Ingredient Review (CIR)Nicotinamide (98-92-0)
InChI1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChIKeyDFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILESNC(=O)c1cccnc1
LogP-0.38 at 21℃
CAS DataBase Reference98-92-0(CAS DataBase Reference)
NIST Chemistry ReferenceNiacinamide(98-92-0)
EPA Substance Registry SystemNicotinamide (98-92-0)

Safety Information

ItemDetails
Hazard CodesXi,T,F
Risk Statements36/37/38-39/23/24/25-23/24/25-11
Safety Statements26-36-37/39-45-36/37-16-7
RIDADRUN1230 - class 3 - PG 2 - Methanol , solution
WGK Germany1
RTECSQS3675000
F8
Autoignition Temperature480 °C
TSCATSCA listed
HS Code29362990
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Hazardous Substances Data98-92-0(Hazardous Substances Data)
ToxicityLD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

Product Application

Niacinamide is a nutrient and dietary supplement that serves as an available form of niacin. Nicotinic acid is pyridine-3-carboxylic acid, and nicotinamide is its corresponding amide. It is a highly water‑soluble powder, with approximately 1 gram dissolving in 1 milliliter of water. Unlike niacin, it has a bitter taste that is masked in encapsulated products. It is widely used for fortifying cereals, snack foods, and powdered beverages. In personal care, it acts as a skin stimulant and skin smoother. USP‑grade nicotinamide is used as a food additive, in multivitamin formulations, and as an intermediate in pharmaceutical and cosmetic manufacturing.

Fast delivery time

Inventory: 2–3 working days.

New production: 7–10 working days.

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