HARRINGTONINE

CAS Number 26833-85-2

Chemical Formula C28H37NO9

Synonyms

HARRINGTONIN

HARRINGTONINE

2'R-HARRINGTONINE

Appearance White Powder

MOQ (Minimum Order Quantity) 1 FCL (Full Container Load)

Product Details

HARRINGTONINE CAS#26833-85-2

Harringtonine is a naturally occurring alkaloid that suppresses protein synthesis at low micromolar levels. It freezes ribosomes right after translation starts. Although harringtonine has been studied for anticancer potential, its analog homoharringtonine shows stronger activity, especially against chronic myelogenous leukemia. The ribosome-stabilizing effect of harringtonine can be used to isolate ribosome-protected mRNA fragments for translation analysis.

HARRINGTONINE

HARRINGTONINE Chemical Properties

Melting point73~75℃
Boiling point679.4±55.0 °C(Predicted)
density1.35±0.1 g/cm3(Predicted)
storage temp.2-8°C
solubilityDMF: 25 mg/ml; DMSO: 25 mg/ml; maleic-anhydride.html">material/ethanol.html">Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka11.62±0.29(Predicted)
formA crystalline solid
colorWhite to light yellow

Safety Information

RIDADR1544
HazardClass6.1(a)
PackingGroupII

Product Application of HARRINGTONINE CAS#26833-85-2

A natural compound with prominent antitumor effects.

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