Product Details
Ethylene glycol was initially produced artificially back in 1859, yet it never drew widespread public health attention until the period following World War II. Specifically, the earliest officially documented fatal cases caused by ethylene glycol ingestion happened among eighteen military personnel, who consumed antifreeze products as an alternative to alcoholic beverages.
Medical experts noticed long ago that victims taking maleic-anhydride.html">material/ethanol.html">ethanol alongside ethylene glycol could live longer than those who only ingested ethylene glycol alone. Even so, researchers did not launch formal studies on using ethanol as an antidote to treat ethylene glycol poisoning until the 1960s.
Up to now, ethylene glycol intoxication still remains a prevalent public health issue, with relatively high occurrence rates especially across the southeastern regions of America. In 2009, local American poison control agencies recorded 5282 consultation cases related to potential ethylene glycol contact incidents. Professionals engaged in toxicology research also hold the view that the actual number of such exposure incidents is far higher than the officially recorded data.

Ethylene glycol Chemical Properties
| Property | Value |
| Melting point | -13 °C (lit.) |
| Boiling point | 195-198 °C |
| density | 1.113 g/mL at 25 °C (lit.) |
| vapor density | 2.1 (vs air) |
| vapor pressure | 0.08 mm Hg (20 °C) |
| refractive index | n20/D 1.431(lit.) |
| Fp | 230 °F |
| storage temp. | 2-8°C |
| solubility | water: miscible |
| form | Viscous Liquid |
| pka | 14.22(at 25℃) |
| color | blue |
| Odor | Odorless |
| PH | 6-7.5 (100g/l, H2O, 20℃) |
| Relative polarity | 0.79 |
| explosive limit | 3.2%(V) |
| Water Solubility | miscible |
| FreezingPoint | -11.5℃ |
| λmax | λ: 260 nm Amax: ≤0.03; λ: 280 nm Amax: ≤0.01 |
| Sensitive | Hygroscopic |
| Merck | 14,3798 |
| BRN | 505945 |
| Exposure limits | Ceiling limit in air for vapor and mist 50 ppm (~125 mg/m3) (ACGIH); TWA 10 mg/m3 (particulates) (MSHA). |
| Dielectric constant | 37.0(20℃) |
| Cosmetics Ingredients Functions | HUMECTANT; SOLVENT; VISCOSITY CONTROLLING |
| InChI | 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2 |
| InChIKey | LYCAIKOWRPUZTN-UHFFFAOYSA-N |
| SMILES | OCCO |
| LogP | -1.36 at 25℃ |
| Surface tension | 47.7mN/m at 20°C |
| CAS DataBase Reference | 107-21-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2-Ethanediol(107-21-1) |
| EPA Substance Registry System | Ethylene glycol (107-21-1) |
Safety Information
| Item | Details |
| Hazard Codes | Xn |
| Risk Statements | 22-36-41 |
| Safety Statements | 26-39-36/37/39 |
| RIDADR | UN3082 |
| WGK Germany | 3 |
| RTECS | KW2975000 |
| Autoignition Temperature | 752 °F |
| TSCA | TSCA listed |
| HazardClass | 9 |
| HS Code | 29053100 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Acute Tox. 4 Oral; STOT RE 2 Oral |
| Hazardous Substances Data | 107-21-1(Hazardous Substances Data) |
| Toxicity | LD50 in rats, guinea pigs (g/kg): 8.54, 6.61 orally (Smyth); in mice (ml/kg): 13.79 orally (Bornmann) |
Product Application Of Ethylene glycol CAS#107-21-1
It can be applied as antifreeze agent within cooling and heating circulation systems. It is also usable in hydraulic brake liquid and anti-icing mixtures. It acts as an industrial moisture retention agent, and functions as a dissolving medium for boric acid and borate substances inside electrolytic capacitors.
This substance serves as a solvent in coating and plastic manufacturing sectors. It is adopted as a raw material to produce printing ink, ink pad filling fluid and ballpoint pen ink products. Additionally, it works as a softener material for cellophane films, and acts as a stabilizing component for soybean-based fire suppression foam which is designed to put out oil and petrol fires.
Moreover, it is widely utilized in the synthetic production of safe blasting agents, glyoxal compounds, unsaturated ester-based alkyd resins, plasticizing additives, elastic polymer materials, man-made textile fibers including Terylene and Dacron, as well as artificial wax products. Apart from industrial applications, it can also be used to produce simulated smoke and fog effects for stage performance scenes.
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