Glycerin

CAS Number: 56-81-5

Official Chemical Name: Glycerol

Alternative Synonyms:

  • Glycerine
  • 1,2,3-Propanetriol

    Molecular Formula: C₃H₈O₃

    Molecular Weight: 92.09

    Appearance: Colorless, transparent viscous liquid

    HS Customs Code: 29054500

    MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

    Sample Supply: Available

Products Description of Glycerin CAS# 56-81-5

Glycerol (also called glycerine) is a simple polyol polyhydric alcohol compound. Pure glycerol is a colorless, odorless viscous liquid with a natural sweet taste.

Key physical constants:

  • Melting Point: 17.9°C
  • Boiling Point: 290°C
  • Relative Density: 1.2613
  • Refractive Index (20°C): 1.4746
  • Closed Cup Flash Point: 177°C

Solubility & hygroscopic characteristics: It can be fully mixed with water at any volume ratio; anhydrous glycerol features strong hygroscopicity and readily absorbs moisture from ambient air. It dissolves freely in low-molecular alcohols, slightly dissolves in diethyl ether, and cannot dissolve in aliphatic and aromatic hydrocarbon solvents.

Chemical stability: Stable under normal room temperature and storage environments, and compatible with most neutral chemical raw materials.

Glycerin

Parameters

ParameterValue
Melting point20 °C(lit.)
Boiling point290 °C
density1.25 g/mL(lit.)
vapor density3.1 (vs air)
vapor pressure<1 mm Hg ( 20 °C)
refractive indexn 20/D 1.474(lit.)
FEMA2525 | GLYCEROL
Fp320 °F
storage temp.Store at +5°C to +30°C.
solubilityH2O: 5 M at 20 °C, clear, colorless
pka14.15(at 25℃)
formViscous Liquid
colorAPHA: ≤10
Specific Gravity1.265 (15/15℃)1.262
OdorOdorless.
PH Range5.5 - 8
PH5.5-8 (25℃, 5M in H2O)
explosive limit2.6-11.3%(V)
Odor Typeodorless
biological sourcesynthetic (organic)
Water Solubility>500 g/L (20 ºC)
SensitiveHygroscopic
λmaxλ: 260 nm Amax: 0.05 λ: 280 nm Amax: 0.04
Merck14,4484
JECFA Number909
BRN635685
Dielectric constant47.0(Ambient)
Exposure limitsOSHA: TWA 15 mg/m3; TWA 5 mg/m3
Stability:Stable. Incompatible with perchloric acid, lead oxide, acetic anhydride, nitrobenzene, chlorine, peroxides, strong acids, strong bases. Combustible.
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
LogP-2.32
Surface tension64mN/m at 20°C
CAS DataBase Reference56-81-5(CAS DataBase Reference)
NIST Chemistry Reference1,2,3-Propanetriol(56-81-5)
EPA Substance Registry SystemGlycerine (56-81-5)
Absorption≤0.02 at 280nm in H2O at 0.5M ≤0.07 at 260nm in H2O at 0.5M

Safety Information

ItemValue
Hazard CodesF,Xn
Risk Statements36-20/21/22-11
Safety Statements24/25-39-26
RIDADRUN 1282 3/PG 2
WGK Germany1
RTECSMA8050000
F3
Autoignition Temperature698 °F
TSCAYes
HS Code29054500
Hazardous Substances Data56-81-5(Hazardous Substances Data)
ToxicityLD50 in rats (ml/kg): >20 orally; 4.4 i.v. (Bartsch)

Product Application of Glycerin CAS# 56-81-5

Glycerol is an indispensable experimental reagent for polyacrylamide gel electrophoresis, mainly applied in sample preprocessing and gel preparation:

  1. Sample loading aid: Adding 5%–10% glycerol to test samples elevates the density of sample solutions, which drives samples to settle at the bottom of gel wells and avoids sample diffusion when loading.
  2. Gradient gel molding additive: It facilitates uniform forming and smooth casting of gradient polyacrylamide gels during gel preparation.
  3. Long-term protein preservation stabilizer: It serves as an efficient protein protective agent, and can be formulated into storage buffer ingredients to sustain native protein activity during long-term low-temperature storage.

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