Oleanolic acid

CAS Number: 508-02-1
Chemical Formula: C30H48O3
Synonyms:
(3-beta)-3-hydroxyolean-12-en-28-oic acid
Oleanolic acid Extract
Olean-12-en-28-oic acid, 3-hydroxy-, (3β)-
Appearance: Yellow powder
HS Code: 29181990
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details

Products Description of Oleanolic acidCAS#508-02-1

Physical & Chemical Properties

This compound presents as fine white crystals under normal temperature. It is practically insoluble in water, while soluble in ethanol, methanol, acetone, chloroform, diethyl ether and other common organic solvents.

Chemically, oleanolic acid can exist in two main forms in nature: free-state acid, or as a typical aglycone of triterpenoid saponins, which is capable of binding with one or multiple sugar chains to form saponin substances. It is biosynthesized from lupane precursors. In chemical conversion reactions, it can undergo isomerization to form ursolic acid, and can also be oxidized to produce taraxasterol and amyrin.

Product Overview

Oleanolic acid is a prevalent natural active ingredient, which is notably found in the non-glyceride fraction of olive pomace oil, as well as abundant in a large variety of edible foods and medicinal plant resources.

Both oleanolic acid itself and its derived derivatives possess multiple valuable biological activities. It features prominent anti-inflammatory performance, and can effectively inhibit secretory phospholipase A2. Beyond anti-inflammatory effects, this compound also delivers remarkable liver protection, strong antioxidant capacity and potential anti-tumor properties, making it a highly functional natural active substance.

Oleanolic acid

Parameters

ItemValue
Melting point>300 °C (lit.)
alphaD20 +83.3° (c = 0.6 in chloroform)
Boiling point502.79°C (rough estimate)
density1.0261 (rough estimate)
refractive index1.4940 (estimate)
storage temp.2-8°C
solubilityChloroform (Very Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka2.52(at 25℃)
formSolid
colorlight yellow
optical activity+83.320(c 0.6, CHCl3)
Merck14,6827
InChIKeyNZQIXFRGWXNLSP-IDYUENATSA-N
LogP8.576 (est)
CAS DataBase Reference508-02-1(CAS DataBase Reference)
EPA Substance Registry SystemOleanolic acid (508-02-1)

Safety Information

ItemValue
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-36-37/39-60-37
WGK Germany2
RTECSRK0177965
TSCAYes
HS Code29181990

Product Application of Oleanolic acidCAS#508-02-1

Oleanolic acid is widely applied in pharmaceutical, health care and related industries due to its outstanding pharmacological activities:

  1. Pharmaceutical Field

    It is the core active ingredient for the treatment of liver diseases. It achieves remarkable curative effects on acute icteric hepatitis, and also shows reliable therapeutic efficacy for chronic hepatitis, so it is commonly used in the development and production of liver-protecting medicines.

  2. Healthcare Products & Dietary Supplements

    Relying on its antioxidant, anti-inflammatory and hepatoprotective functions, it is extensively added into health supplements to assist with body conditioning and daily liver care.

  3. Other Industrial Uses

    With its comprehensive biological activities, it is also used as a functional additive in the research and development of plant-based preparations and related fine chemical products.

Factory and Equipment Show

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Inventory 2-3 working days New production 7-10 working days

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