Products Description
Dexamethasone ranks among the most widely used medications in clinical settings. It is frequently administered in combination with other pharmaleic-anhydride.html">maceutical agents. It exhibits anti-inflammatory, anti-toxic, and anti-allergic properties. It does not cure underlying diseases but only reduces or suppresses inflammatory responses. This point requires special attention in clinical practice; it is generally not used alone and should be combined with other drugs to achieve optimal therapeutic effects.
Chemical Properties
| Parameter | Value |
| Melting point | 262-264 °C (lit.) |
| alpha | 75 º (c=1, dioxane) |
| Boiling point | 568.2±50.0 °C(Predicted) |
| density | 1.1283 (estimate) |
| refractive index | 76 ° (C=1, Dioxane) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 mg/mL |
| form | powder |
| pka | 12.13±0.70(Predicted) |
| color | off-white |
| biological source | synthetic (organic) |
| Water Solubility | 10 mg/100 mL (25 ºC) |
| Sensitive | Light Sensitive |
| Merck | 142943 |
| BRN | 2066651 |
| BCS Class | 1 (CLogP), 3 (LogP) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. |
| InChIKey | UREBDLICKHMUKA-CXSFZGCWSA-N |
| CAS DataBase Reference | 50-02-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) |
| EPA Substance Registry System | Dexamethasone (50-02-2) |
Safety Information
| Item | Value |
| Hazard Codes | Xi,Xn,T,F |
| Risk Statements | 43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-36-26-22-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | TU3980000 |
| TSCA | Yes |
| HS Code | 29372210 |
| Hazardous Substances Data | 50-02-2(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: > 3gm/kg |
Product Application
Dexamethasone (dexamethasone sodium phosphate EP impurity A) is a glucocorticoid applied as an anti-inflammatory agent. It modulates the survival, growth, and differentiation of T cells. It also blocks the induction of nitric oxide synthase. It is primarily applied for anti-inflammatory and anti-allergic purposes, and is indicated for rheumatoid arthritis and other collagen-related disorders.
Supply & Delivery
Fast delivery time
Inventory: 2-3 working days
New production: 7-10 working days
