Glycyrrhizic acid ammonium salt

CAS Number: 53956-04-0
Chemical Formula: C42H65NO16
Synonyms:
Glycyrrhizine ammonium salt
Monoammoniumglycyrrhetate
Monoammoniumglycyrrhizate
Appearance: Yellow Powder
HS Code: 29389090
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details

Products Description of Glycyrrhizic acid ammonium saltCAS#53956-04-0
Ammonium Glycyrrhizinate features a strong sweet taste, roughly 200 times sweeter than sucrose. It is widely used as a sweetener in food additives, including canned meats, flavorings, candies, biscuits, preserved fruits, and drinks. Monoammonium glycyrrhizinate shows strong binding to hepatic sterol‑metabolizing enzymes, which helps prevent the breakdown of cortisol and aldosterone. When used, it provides noticeable glucocorticoid‑like benefits such as anti‑inflammaleic-anhydride.html">matory and anti‑allergic effects and cell membrane protection, without the usual side effects of corticosteroid medicines.

Glycyrrhizic acid ammonium salt

Parameters

ItemValue
Melting point>200°C (dec.)
Boiling point768.56°C (rough estimate)
density1.1846 (rough estimate)
FEMA2528 | GLYCYRRHIZIN, AMMONIATED (GLYCYRRHIZA SPP.)
refractive index49 ° (C=1.5, EtOH)
storage temp.2-8°C
solubilitySlightly soluble in water, very slightly soluble in anhydrous ethanol, practically insoluble in acetone. It dissolves in dilute solutions of acids and of alkali hydroxides.
formPowder or Crystals
colorYellow to yellow-green
Odorbland
optical activity[α]20/D +48±4°, c = 1% in ethanol: water (1:1)
BRN3897076
StabilityHygroscopic
InChIKeyILRKKHJEINIICQ-YDYGGSECSA-N
LogP-0.9
CAS DataBase Reference53956-04-0
EPA Substance Registry System.alpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-, monoammonium salt (53956-04-0)

Safety Information

ItemValue
RIDADRUN 3077 9 / PGIII
WGK Germany2
RTECSLZ6500000
F3-10
HS Code29389090

Product Application of Glycyrrhizic acid ammonium salt CAS#53956-04-0

Ammonium Glycyrrhizinate is used in making polyion complex nanocarriers, which can serve as a blueprint for developing other water‑soluble drugs with negative charges. It works well with many anti‑inflammatory drugs. It is a flavor and sweet ingredient derived from licorice flavonoids, offering mild licorice taste and full‑bodied sweetness. It dissolves in water, glycerol.html">glycerin, and propylene glycol, with good heat stability, though long heating may cause degradation. It stays stable at pH 3.5–9 but may precipitate below pH 3.5. Suitable uses include drinks, desserts, confectionery, soups, and sauces.
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